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KMID : 0390220020130010130
Journal of Clinical Otolaryngology, Head and Neck Surgery
2002 Volume.13 No. 1 p.130 ~ p.134
A Case of the Olfactory Neuroblastoma
Moon Seung-Il

Shim Hyun-Joon
Kwon Soon-Uk
Yoon Sang-Won
Abstract
Olfactory neuroblastoma is uncommon neuroendocrine malignant tumor originated from olfactory epithelium of neural crest in the upper portion of nasal cavity. This tumor account for 2% of all malignant nasal neoplasm and early involves the cribriform plate and rapidly penetrate into the anterior cranial fossa. The meatastasis develope in the neck, lymph node, lung, bone and so on from 20% to 42%. Although the principle of treatment is not established yet, combined therapy of surgery and radiation is generally recommended. We have experienced one case of neuroblastoma localized in the nasal cavity and nearly completely removed via transpalatal and transnasal approach followed by radiotherapy. At this time the tumor is not recurred and any complication has been not developed, so we report this case with review of the literature.
KEYWORD
Neuroblastoma, Nasal cavity
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